- Create and save custom Primer Extensions: Choose sequences from your Geneious database to use as primer extensions when designing primers, with annotations carried through to your PCR products.
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Advanced Cloud Workflow sharing: Save workflows in the Cloud, and share them with colleagues. You can now share Cloud Workflows with specific people or groups within your organisation, in read-only mode.
New Release
Geneious Prime 2025.2
2025-07-15

Geneious Prime 2025.1
2025-03-12
- Apple Silicon: Speed up your analyses by up to 40% or more on macOS with Geneious Prime now running natively on Apple Silicon (ARM64 architecture).
- Cloning Validation Enhancements: Easily group and batch align your sequencing data to virtual clones with usability and performance improvements to the cloning validation tool.
- Cloud Workspace: Backup your data and streamline collaboration in the cloud. This release includes performance improvements, support for restoring Deleted Items, and extended sharing options.
Geneious Prime 2025.0
2024-10-31

- QC Report for NGS Sequences: Quickly visualise overall NGS data quality in the new QC Report tab, calculated using the FastQC tool from Babraham Bioinformatics.
- Geneious Cloud: Backup your data and streamline collaboration with significant performance enhancements and improved sharing options for Geneious Cloud.
Geneious Prime 2024.0
2024-02-14
- Cloning Validation: New visual and semi-automated step to add, export and record validation metadata during batch plasmid validation.
- Map to Reference Algorithm Advisor: Interactive quiz to help you decide which algorithm is the best fit for you data.
Geneious Prime 2023.2
2023-07-12
- De Novo Assembly Algorithm Advisor: Interactive quiz to help you decide which algorithm is the best fit for your data.
- Cloud Personal Workspace: Access your data from multiple computers with secure personal data storage in Geneious Prime.
- Export Lengths Graph Data: Quickly and easily export a csv file with your sequence length distribution data.
- Improvements to STAR RNA-seq aligner: You can now use the STAR RNA-seq aligner in Geneious with multiple references.
Geneious Prime 2023.1
2023-04-03

- Dotmatics Platform Integration plugin: Launch the registration workflow to register your sequences in Dotmatics Bioregister.
- Import .sbd files: Geneious Prime can now import DNAStar Lasergene SeqBuilder(Pro) .sbd file format.
- Geneious Cloud Database: Access your data from multiple computers with secure personal data storage in Geneious Prime.
Geneious Prime 2023.0
2022-11-29
- Primer Specificity Testing: Design target-specific primers in one step with new primer specificity testing.
- Cloning Validation: New visual tool for automating sequence alignment during batch plasmid validation
- STAR RNA-seq mapper: Added STAR, a RNA-seq mapper that performs highly accurate spliced sequence alignment.
- CRISPR Improvements: Added more PAMs and the ability to select individual sequences for specificity testing.
Geneious Prime 2022.2
2022-07-11
- In-Fusion cloning: Perform low or high throughput In-Fusion Cloning with pre-optimized settings.
- Parts Cloning Support for Proteins: Scale up your construct engineering with combinatorial assembly of proteins.
- Primer Extension Detection: Automatically detect and annotate extensions on your primer databases during import.
Geneious Prime 2022.1
2022-03-14
- Batch Golden Gate: Perform Golden Gate cloning in batch using sequence lists and stop doing your Golden Gate cloning operations one by one.
- Parts Cloning: Scale up your cloning throughput with added support for Parts Cloning, combining every possible combination from your lists of parts.
- Primer Import: Easily import and characterize primer databases stored in excel spreadsheets so you can take full advantage of the primer tool suite, including Test with Saved Primers.
Geneious Prime 2022.0
2021-11-15
- Annotate by BLAST: Automatically annotate your ORFs, CDS and mRNA regions using BLAST.
- Command Line Interface: Run Geneious Prime operations and workflows as part of your broader bioinformatic pipelines locally or execute on more powerful servers.
- Dark Mode: Comfortably analyze your data at any time of the day or night with Geneious Prime in dark mode
- Experimental Features: Try out features we are experimenting with and let us know your thoughts
- Apply Optimized Codon: Easily add and remove optimized codons to your sequence
- Manage Document Table Columns: Quickly organize your data with multiple column selection
- Highlight Mismatching Bases: Highlight mismatching base calls in your chromatograms
Geneious Prime 2021.2
2021-07-12
- Virtual gel improvements: Easily view multiple sequences with the display of restriction enzymes in lane headings, and quick access to an exportable list of fragments
- View CRISPR cut sites: Easily view and compare CRISPR cut sites between your guide RNAs
- View invalid CDS annotations: Improve your cloning workflows by quickly determining CDS annotations with premature stop codons
- Batch edit annotations: Quickly add or edit annotations in batch by copying properties from other annotations, sequences or documents
Geneious Prime 2021.1
2021-03-15
- New filter interface: Locate documents quickly in any table with the new filter button added to the status bar.
- Adjustable sequence selection: Adjust either end of the selected region in the Sequence View by dragging.
- Amino acid numbering: Live numbering can now be shown alongside the translated amino acids on nucleotide sequences.
Geneious Prime 2021.0
2020-11-30
- Geneious Prime gets a new look: Enjoy the new look and feel of Geneious Prime with an updated design, including new icons and font.
- Highlighted methylation sites for restriction enzymes: Quickly visualize restriction sites affected by Dam, Dcm and EcoKI methylation.
- Accessible sequence viewer statistics: Easily sort and export your protein and nucleotide statistics within the document table.
- New CRISPR on-target scoring method: Confidently design your guide RNAs using the Doench et al. 2016 CRISPR on-target scoring algorithm.
Geneious Prime 2020.2
2020-07-13
Geneious Prime 2020 brings exciting new functionality to transform raw sequence data into meaningful visualizations.
- Analyze CRISPR Editing Results
- Enhanced Search Options
- Codon Optimization Improvements
Geneious Prime 2020.1
2020-03-09
Geneious Prime 2020.1 brings exciting new functionality to transform raw sequence data into meaningful visualizations.
- Long-read de novo Assembly with Flye (external plugin)
- Import Metadata on to Sequences and other Documents
- Codon Optimization and Back Translation Improvements
- Primer Specificity Testing
Geneious Prime 2020.0
2019-11-04
Geneious Prime 2020 brings exciting new functionality to transform raw sequence data into meaningful visualizations.
- Clustal Omega replaces ClustalW for better, faster alignments
- Better back translate and codon optimization
- More accurate annotation of CDS features onto your plasmids
- Long-read sequence mapping with Minimap2 (external plugin)
- Add your favorite tools to Geneious with improved Wrapper Plugin system
Geneious Prime 2019.2
2019-06-17
Geneious Prime 2019 brings powerful analyses to increase accuracy and help transform collaboration.
- Restriction Enzymes
- Sanger Sequencing Primer Design
- Easier Shared Database Rollout
- Improved Text View Formatting of Sequences and Alignments
Geneious Prime 2019.1
2019-03-04
Geneious Prime 2019 brings powerful analyses to increase accuracy and help transform collaboration.
- Customizable Text View
- Primer Specificity
- Primer Design Improvements
- Vector NTI Database Import
Geneious Prime 2019.0
2018-10-22
Geneious Prime 2019 brings powerful analyses to increase accuracy and help transform collaboration.
- Custom Codon Usage Tables
- Rapid Manual Primer Design
- Powerful Primer Annotation Display
- Simplified Testing and Annotation of Existing Primers
- Drag and Drop Sequence Export
- Easy Extraction of PCR and Restriction Digest Products
- Improved Protein Statistics
- Improved GenBank Export
- Publish Plugins via Internal Network